Click on the hallmark of interest, e.g. “Neutrophils COVID severity”, and you will be taken to a new page to explore these features
Clicking the feature of interest from within the panel will plot individual markers (e.g. expression of single genes) on the right hand side
Clicking another feature will add a new plot on the RHS
Features comprising multiple markers, e.g. pathways will display a heatmap on the top left, which can be clicked in turn to display plots for individual features on the right hand side
Additional hallmarks may be added for comparison using the “Load Data” button on the top left
Example Workflow 2: visualising single cell gene expression data
Click on the “visualise gene expression” button for single cell gene expression (CITE-seq)
Paste in the gene(s) of interest
A heatmap will be displayed, showing the expression of this gene set across all samples in a particular cell type (by default B.INT)
By clicking on a node in the cell hierarchy dendrogram, you can change for which cell type data is shown
Clicking on a gene name in the heatmap will give you a boxplot on the right showing expression in the selected cell type, and a heatmap showing expression across all available cell types
You can change which comparator groups are shown across all plots by clicking on the “Source” barchart on the right